Stephan Warnat ME Faculty Candidate - Research Seminar
- Thursday, February 23, 2017 at 11:00am
- Roberts Hall - view map
Estimation of Mechanical Cell Properties using MEMS and Microfluidics for Environmental Applications
Abstract: Water monitoring with a large spatial and temporal density is currently only limited possible due to high costs for equipment and labor. Changes of the marine ecosystem are therefore often observed too late and can cause large economic loss in aquaculture or tourism. Micro-Electromechancial systems (MEMS) and microfluidics offer the opportunity to establish remote sensing platforms to observe water quality in real time and low cost and will allow environmental scientist to investigate and predict dynamic changes of the marine ecosystem.
Monitoring the mechanical cell stiffness of single cells is one indicator (biomarker) to characterize water quality. This talk presents a Micro-Electromechemical System (MEMS) to measure this property on single cell level and discusses system integration challenges: 1) An approach will be discussed to determine the mechanical cell stiffness and physiology based on differential displacement measurements using MEMS. Displacements were measured optically within a ±10 nm accuracy during operation in aqueous media; 2) A reliability study of MEMS devices in an aqueous media will be discussed; 3) Challenges of the system integration using a novel Gecko inspired adhesive technology are presented.
I will conclude the talk with future work to integrate new MEMS and microfluidic components into a mobile monitoring platform and show how undergraduate and graduate students can benefit from this work.
Bio: Dr. Warnat received his PhD from the Department of Material Science at the Christian Albrechts University of Kiel, Germany, in 2010. His research was conducted at the internationally noted Fraunhofer Institute of Silicon Technology and he developed innovative technologies and fabrication flows for Through Silicon Vias (TSV) in Micro-Electromechanical Systems (MEMS). From 2009 to 2012, he established a Fraunhofer research group at the Christian Albrechts University of Kiel. In 2012, he received a prestigious scholarship from the German Research Foundation to perform research at Dalhousie University in Halifax, NS. Dr. Warnat holds the status of an Adjunct Professor granted from the Department of Mechanical Engineering at Dalhousie University since 2016. His research activities encompass the areas of microfabrication, microfluidics, sensors and actuators to investigate mechanical cell properties in aqueous media with applications in environmental monitoring. Dr. Warnat has co-authored more than 20 journal and conference publications. He holds two patents.